18 Years Factory Canagliflozin Dosage - Pitavastatin Calcium – CPF
18 Years Factory Canagliflozin Dosage - Pitavastatin Calcium – CPF Detail:
匹伐他汀钙 | Pitavastatin | 147526-32-7 | In-House |
PI-5 | 3800-06-4 | In-House | |
PI-6 | 145516-11-4 | In-House | |
PI-7 | 121660-11-5 | In-House |
Description
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
Background
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
Storage
4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Chemical structure
Related Biological Data
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Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
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Our aim would be to fulfill our shoppers by offering golden company, very good value and good quality for 18 Years Factory Canagliflozin Dosage - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: Haiti, Poland, South Korea, Being the top solutions of our factory, our solutions series have been tested and won us experienced authority certifications. For additional parameters and item list details, please click the button to acquire additional nformation.
By Laura from Irish - 2017.10.27 12:12
We are really happy to find such a manufacturer that ensuring product quality at the same time the price is very cheap.
By Caroline from Sao Paulo - 2018.06.30 17:29