2020 High quality Fxr Agonist Obeticholic Acid - Chlorothiazide – CPF
2020 High quality Fxr Agonist Obeticholic Acid - Chlorothiazide – CPF Detail:
Background
Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions.
Description
Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often taken in pill form, it is usually taken orally once or twice a day. In the ICU setting, chlorothiazide is given to diurese a patient in addition to furosemide (Lasix). Working in a separate mechanism than furosemide, and absorbed enterically as a reconstituted suspension administered through a nasogastric tube (NG tube), the two drugs potentiate one another.
Clinical Trial
NCT Number | Sponsor | Condition | Start Date |
Phase |
NCT03574857 | University of Virginia | Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure Acute|Cardiovascular Diseases | June 2018 |
Phase 4 |
NCT02546583 | Yale University|National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure | August 2015 |
Not Applicable |
NCT02606253 | Vanderbilt University|Vanderbilt University Medical Center | Heart Failure | February 2016 |
Phase 4 |
NCT00004360 | National Center for Research Resources (NCRR)|Northwestern University|Office of Rare Diseases (ORD) | Diabetes Insipidus, Nephrogenic | September 1995 |
|
NCT00000484 | National Heart, Lung, and Blood Institute (NHLBI) | Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases | April 1966 |
Phase 3 |
Chemical structure
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
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International cooperation
Domestic cooperation
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Our staff through skilled training. Skilled skilled knowledge, potent sense of company, to satisfy the provider requirements of consumers for 2020 High quality Fxr Agonist Obeticholic Acid - Chlorothiazide – CPF , The product will supply to all over the world, such as: Cambodia, Egypt, Lisbon, We've a good reputation for stable quality solutions, well received by customers at home and abroad. Our company would be guided by the idea of "Standing in Domestic Markets, Walking into International Markets". We sincerely hope that we could do business with customers both at home and abroad. We expect sincere cooperation and common development!
By Kimberley from Turkmenistan - 2018.06.05 13:10
This is the first business after our company establish, products and services are very satisfying, we have a good start, we hope to cooperate continuous in the future!
By Bella from United Kingdom - 2017.05.31 13:26