Best quality Doxycycline Mono 100mg Acne - Pitavastatin Calcium – CPF
Best quality Doxycycline Mono 100mg Acne - Pitavastatin Calcium – CPF Detail:
匹伐他汀钙 | Pitavastatin | 147526-32-7 | In-House |
PI-5 | 3800-06-4 | In-House | |
PI-6 | 145516-11-4 | In-House | |
PI-7 | 121660-11-5 | In-House |
Description
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
Background
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
Storage
4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Chemical structure
Related Biological Data
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We pursue the administration tenet of "Quality is exceptional, Provider is supreme, Name is first", and will sincerely create and share success with all clientele for Best quality Doxycycline Mono 100mg Acne - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: azerbaijan, Japan, Houston, Our company's main products are widely used all over the world; 80% of our products exported to the United States, Japan, Europe and other markets. All stuff sincerely welcome guests come to visit our factory.
By Murray from Romania - 2017.12.09 14:01
Timely delivery, strict implementation of the contract provisions of the goods, encountered special circumstances, but also actively cooperate, a trustworthy company!
By Julia from Austria - 2017.09.22 11:32