China China wholesale Hydrochlorothiazide Manufacturer - Pitavastatin Calcium – CPF manufacturers and suppliers

China wholesale Hydrochlorothiazide Manufacturer - Pitavastatin Calcium – CPF

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Our merchandise are broadly identified and trusted by end users and can satisfy continually developing economic and social requires for Rosuvastatin Calcium 10, Daclatasvir 60 Mg, Doxycycline Hyclate 100 Mg Tab Tablet, We are confident that there will be a promising future and we hope we can have long term cooperation with customers from all over the world.

China wholesale Hydrochlorothiazide Manufacturer - Pitavastatin Calcium – CPF Detail:

匹伐他汀钙	Pitavastatin	147526-32-7	In-House
PI-5		3800-06-4	In-House
PI-6		145516-11-4	In-House
PI-7		121660-11-5	In-House

Description

Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.

Background

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Chemical structure

Pitavastatin Calcium

Related Biological Data

Pitavastatin Calcium2

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.

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International cooperation

Domestic cooperation

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We keep on with our enterprise spirit of "Quality, Efficiency, Innovation and Integrity". We intention to create extra worth for our buyers with our prosperous resources, superior machinery, experienced workers and superb services for China wholesale Hydrochlorothiazide Manufacturer - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: Nicaragua, Greek, Lebanon, To create more creative products, maintain high-quality products and update not only our products but ourselves so as to keep us ahead of the world, and the last but most vital one: to make every client satisfied with everything we offer and to grow stronger together. To be the real winner, starts here!

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Rosuvastatin Calcium 5 Mg Tab

Rosuvastatin Calcium Use

We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.