China China Wholesale Rosuvastatin Calcium 20 Manufacturers - Pitavastatin Calcium – CPF manufacturers and suppliers

China Wholesale Rosuvastatin Calcium 20 Manufacturers - Pitavastatin Calcium – CPF

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We provide good power in high-quality and progress,merchandising,revenue and internet marketing and operation for Doxycycline Hyclate 100mg For Chlamydia, Doxycycline Hyclate Dr, Doxycycline Monohydrate 100 Mg Oral Capsule, We are keeping durable small business relationships with additional than 200 wholesalers in the USA, the UK, Germany and Canada. For anyone who is intrigued in any of our products, make sure you experience free to speak to us.

China Wholesale Rosuvastatin Calcium 20 Manufacturers - Pitavastatin Calcium – CPF Detail:

匹伐他汀钙	Pitavastatin	147526-32-7	In-House
PI-5		3800-06-4	In-House
PI-6		145516-11-4	In-House
PI-7		121660-11-5	In-House

Description

Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.

Background

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Chemical structure

Pitavastatin Calcium

Related Biological Data

Pitavastatin Calcium2

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.

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Our eternal pursuits are the attitude of "regard the market, regard the custom, regard the science" as well as the theory of "quality the basic, believe in the 1st and management the advanced" for China Wholesale Rosuvastatin Calcium 20 Manufacturers - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: Ireland, Slovenia, Austria, We've got constantly insisted on the evolution of solutions, spent good funds and human resource in technological upgrading, and facilitate production improvement, meeting the wants of prospects from all countries and regions.

China Wholesale Calcium Rosuvastatin Manufacturers