English

China Wholesale Rosuvastatin Calcium 40 Mg Tab Factory - Canagliflozin – CPF

China Wholesale Rosuvastatin Calcium 40 Mg Tab Factory - Canagliflozin – CPF Featured Image
  • China Wholesale Rosuvastatin Calcium 40 Mg Tab Factory - Canagliflozin – CPF

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

We've numerous great employees customers excellent at promoting, QC, and working with kinds of troublesome difficulty inside the generation method for Ezetimibe, Rosuvastatin Calcium Generic, Doxycycline Monohydrate 100mg Uses, We've been honest and open up. We glance ahead on your pay a visit to and developing trustworthy and long-term standing relationship.
China Wholesale Rosuvastatin Calcium 40 Mg Tab Factory - Canagliflozin – CPF Detail:

Background

Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2].

Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1].

Canagliflozin has been reported to reduce the blood glucose (BG) levels dose-dependently in both db/db Mice and Zucker diabetic fatty (ZDF) Rats. Additionally, canagliflozin has proved to decrease the respiratory exchange ratio, and body weight in DIO mice and ZDF rats [1].

Canagliflozin can be taken orally [1].

References:
[1] Liang Y1, Arakawa K, Ueta K, Matsushita Y, Kuriyama C Martin T, Du F, Liu Y, Xu J, Conway B, Conway J, Polidori D, Ways K, Demarest K. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. PLoS One. 2012;7(2):e30555
[2] Sarnoski-Brocavich S, Hilas O. Canagliflozin (Invokana), a Novel Oral Agent For Type-2 Diabetes. P T. 2013 Nov;38(11):656-66

Product Citation

Bahia Abbas Moussa, Marianne Alphonse Mahrouse, et al. “Different resolution techniques for management of overlapped spectra: Application for the determination of novel co-formulated hypoglycemic drugs in their combined pharmaceutical dosage form.” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Available online 20 June 2018.

Chemical structure

Canagliflozin

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect. 

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.


VIEW MORE


VIEW MORE

International cooperation
International cooperation
Domestic cooperation
Domestic cooperation

Product detail pictures:

China Wholesale Rosuvastatin Calcium 40 Mg Tab Factory - Canagliflozin – CPF detail pictures

Related Product Guide:
We offer wonderful energy in high-quality and improvement,merchandising,product sales and marketing and advertising and procedure for China Wholesale Rosuvastatin Calcium 40 Mg Tab Factory - Canagliflozin – CPF , The product will supply to all over the world, such as: Ireland, Guatemala, Lithuania, With more and more Chinese products and solutions around the world, our international business is developing rapidly and economic indicators big increase year by year. We have enough confidence to supply you both better solutions and service, because we've been more and more powerful, specialist and experience in domestic and international.
    • The sales person is professional and responsible, warm and polite, we had a pleasant conversation and no language barriers on communication.
    5 Stars By Flora from Nigeria - 2017.10.13 10:47
    The company can keep up with the changes in this industry market, product updates fast and the price is cheap, this is our second cooperation, it's good.
    5 Stars By Camille from Cape Town - 2017.06.25 12:48
    Write your message here and send it to us

    Products categories