China Wholesale Ticagrelor Factory - Captopril – CPF
China Wholesale Ticagrelor Factory - Captopril – CPF Detail:
Description
Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE).
In Vitro
Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the cis and trans states of Captopril (SQ-14534) exists in solution and that the enzyme selects only the trans state of the inhibitor that presents architectural and stereoelectronic complementarity with its substrate binding groove[2].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
NCT Number | Sponsor | Condition | Start Date |
Phase |
NCT03179163 | Penn State University|National Heart, Lung, and Blood Institute (NHLBI) | Hypertension,Essential | July 20, 2016 |
Phase 1|Phase 2 |
NCT03660293 | Tanta University | Diabetes Mellitus, Type 1 | April 1, 2017 |
Not Applicable |
NCT03147092 | Centro Neurológico de Pesquisa e Reabiitação, Brazil | Hypertension|Blood Pressure | February 1, 2018 |
Early Phase 1 |
NCT00252317 | Rigshospitalet, Denmark | Aortic Stenosis | November 2005 |
Phase 4 |
NCT02217852 | West China Hospital | Hypertension | August 2014 |
Phase 4 |
NCT01626469 | Brigham and Women´s Hospital | Type 2 Diabetes Mellitus | May 2012 |
Phase 1|Phase 2 |
NCT00391846 | AstraZeneca | Heart Failure|Ventricular Dysfunction, Left | October 2006 |
Phase 4 |
NCT00240656 | Hebei Medical University | Hypertension, Pulmonary | October 2005 |
Phase 1 |
NCT00086723 | Northwestern University|National Cancer Institute (NCI) | Unspecified Adult Solid Tumor, Protocol Specific | July 2003 |
Phase 1|Phase 2 |
NCT00663949 | Shiraz University of Medical Sciences | Diabetic Nephropathy | February 2006 |
Phase 2|Phase 3 |
NCT01437371 | University Hospital, Clermont-Ferrand|Servier|LivaNova | Heart Failure | August 2011 |
Phase 3 |
NCT04288700 | Ain Shams University | Infantile Hemangioma | October 1, 2019 |
Phase 4 |
NCT00223717 | Vanderbilt University|Vanderbilt University Medical Center | Hypertension | January 2001 |
Phase 1 |
NCT02770378 | University of Ulm|Reliable Cancer Therapies|Anticancer Fund, Belgium | Glioblastoma | November 2016 |
Phase 1|Phase 2 |
NCT01761916 | Instituto Materno Infantil Prof. Fernando Figueira | Preeclampsia | January 2013 |
Phase 4 |
NCT01545479 | Instituto de Cardiologia do Rio Grande do Sul | Renal Disease | January 2010 |
Phase 4 |
NCT00935805 | Hospital de Clinicas de Porto Alegre|Conselho Nacional de Desenvolvimento Científico e Tecnológico|Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil | Diabetes Mellitus|Arterial Hypertension | July 2006 |
|
NCT00742040 | The Hospital for Sick Children | Heart Disease | August 2008 |
Phase 2 |
NCT03613506 | Wuhan University | Radiotherapy Side Effect|Taking Captopril | October 25, 2018 |
Phase 2 |
NCT00004230 | Northwestern University|National Cancer Institute (NCI) | Cancer | October 1999 |
Phase 3 |
NCT00660309 | Novartis | Type 2 Diabetes Mellitus | April 2008 |
Phase 4 |
NCT00292162 | NHS Greater Glasgow and Clyde | Chronic Heart Failure|Atrial Fibrillation | January 2007 |
Not Applicable |
NCT01271478 | Coordinación de Investigación en Salud, Mexico | Inflammation|End-stage Renal Disease | August 2009 |
Phase 4 |
NCT04193137 | Chongqing Medical University | Primary Aldosteronism | November 30, 2019 |
|
NCT00155064 | National Taiwan University Hospital | Hyperaldosteronism | July 2002 |
Phase 4 |
NCT01292694 | Vanderbilt University|Vanderbilt University Medical Center | Hypertension|Pure Autonomic Failure|Multiple System Atrophy | March 2011 |
Phase 1 |
NCT00917345 | National Taiwan University Hospital|Novartis | Primary Aldosteronism | January 2008 |
|
NCT00077064 | Radiation Therapy Oncology Group|National Cancer Institute (NCI)|NRG Oncology | Lung Cancer|Pulmonary Complications|Radiation Fibrosis | June 2003 |
Phase 2 |
Storage
Powder |
-20°C |
3 years |
4°C |
2 years | |
In solvent |
-80°C |
6 months |
-20°C |
1 month |
Chemical structure
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
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International cooperation
Domestic cooperation
Product detail pictures:
Related Product Guide:
"Sincerity, Innovation, Rigorousness, and Efficiency" is the persistent conception of our company for the long-term to develop together with customers for mutual reciprocity and mutual benefit for China Wholesale Ticagrelor Factory - Captopril – CPF , The product will supply to all over the world, such as: St. Petersburg, New Orleans, Luxemburg, Qualified R&D engineer might be there for your consultation service and we will try our best to meet your requirements. So you should feel free to contact us for inquiries. You'll be able to send us emails or call us for small business. Also you are able to come to our business by yourself to get further knowing of us. And we are going to surely present you with the best quotation and after-sale service. We're ready to build stable and friendly relations with our merchants. To achieve mutual success, we'll make our best efforts to build a solid co-operation and transparent communication work with our companions. Above all, we're here to welcome your inquiries for any of our merchandise and service.
By Mavis from Tunisia - 2018.11.11 19:52
The factory workers have rich industry knowledge and operational experience, we learned a lot in working with them,we are extremely grateful that we can encount a good company has excellent wokers.
By Afra from United Arab emirates - 2018.09.16 11:31