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Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Canagliflozin – CPF

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  • Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Canagliflozin – CPF

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With responsible good quality method, good status and excellent client services, the series of solutions produced by our company are exported to lots of countries and regions for Fxr Agonist Obeticholic Acid, Venetoclax Manufacturer, Doxycycline Hyclate 100mg Capsules Uses, Encouraged with the fast producing current market on the speedy foodstuff and beverage consumables all around the entire world , We're hunting forward to functioning with partners/clients to create good results together.
Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Canagliflozin – CPF Detail:

Background

Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2].

Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1].

Canagliflozin has been reported to reduce the blood glucose (BG) levels dose-dependently in both db/db Mice and Zucker diabetic fatty (ZDF) Rats. Additionally, canagliflozin has proved to decrease the respiratory exchange ratio, and body weight in DIO mice and ZDF rats [1].

Canagliflozin can be taken orally [1].

References:
[1] Liang Y1, Arakawa K, Ueta K, Matsushita Y, Kuriyama C Martin T, Du F, Liu Y, Xu J, Conway B, Conway J, Polidori D, Ways K, Demarest K. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. PLoS One. 2012;7(2):e30555
[2] Sarnoski-Brocavich S, Hilas O. Canagliflozin (Invokana), a Novel Oral Agent For Type-2 Diabetes. P T. 2013 Nov;38(11):656-66

Product Citation

Bahia Abbas Moussa, Marianne Alphonse Mahrouse, et al. “Different resolution techniques for management of overlapped spectra: Application for the determination of novel co-formulated hypoglycemic drugs in their combined pharmaceutical dosage form.” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Available online 20 June 2018.

Chemical structure

Canagliflozin

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect. 

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.


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The organization upholds the philosophy of "Be No.1 in good quality, be rooted on credit history and trustworthiness for growth", will keep on to provide previous and new customers from home and overseas whole-heatedly for Factory Outlets Blood Pressure Medicine Hydrochlorothiazide - Canagliflozin – CPF , The product will supply to all over the world, such as: Marseille, Macedonia, Jersey, Since the establishment of our company, we have realized the importance of providing good quality products and the best before-sales and after-sales services. Most problems between global suppliers and clients are due to poor communication. Culturally, suppliers can be reluctant to question things they do not understand. We break down those barriers to ensure you get what you want to the level you expect, when you want it.
    • The supplier abide the theory of "quality the basic, trust the first and management the advanced" so that they can ensure a reliable product quality and stable customers.
    5 Stars By Elsa from Georgia - 2018.05.15 10:52
    Perfect services, quality products and competitive prices, we have work many times, every time is delighted, wish continue to maintain!
    5 Stars By Martina from Florence - 2017.11.29 11:09
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