Factory Price Doxycycline Hyclate Español - Rosuvastatin Calcium – CPF
Factory Price Doxycycline Hyclate Español - Rosuvastatin Calcium – CPF Detail:
瑞舒伐他汀钙 | Rosuvastatin Calcium | 147098-20-2 | In-House/CEP |
RSM(Crystal) | 147118-40-9 | In-House | |
RSM(Crude) | 147118-40-9 | In-House | |
RSP | — | In-House | |
RS-8 | 147118-36-3 | In-House | |
RS-8-1 | 147118-37-4 | In-House | |
TP-8 | 131466-61-0 | In-House | |
TP-11 | 147118-35-2 | In-House | |
TP-13 | 147118-39-6 | In-House | |
RS-10 | 289042-12-2 | In-House | |
RS-11 | 355806-00-7 | In-House |
Description
Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. and a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM[1]. Rosuvastatin Calcium potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals[2]. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[3].
Further information on drug naming conventions: International Nonproprietary Names.
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In the US, Rosuvastatin (rosuvastatin systemic) is a member of the drug class statins and is used to treat Atherosclerosis, High Cholesterol, High Cholesterol – Familial Heterozygous, High Cholesterol – Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa – Elevated LDL, Hyperlipoproteinemia Type IIb – Elevated LDL VLDL, Hyperlipoproteinemia Type III – Elevated beta-VLDL IDL, Hyperlipoproteinemia Type IV – Elevated VLDL, Hypertriglyceridemia and Prevention of Cardiovascular Disease.
Background
A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic.
Storage
Powder |
-20°C |
3 years |
4°C |
2 years | |
In solvent |
-80°C |
6 months |
-20°C |
1 month |
Chemical structure
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
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International cooperation
Domestic cooperation
Product detail pictures:
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Our company puts emphasis on the management, the introduction of talented personnel, and the construction of staff building, trying hard to improve the quality and liability consciousness of staff members. Our company successfully attained IS9001 Certification and European CE Certification of Factory Price Doxycycline Hyclate Español - Rosuvastatin Calcium – CPF , The product will supply to all over the world, such as: London, Qatar, Argentina, We focus on providing service for our clients as a key element in strengthening our long-term relationships. Our continual availability of high grade products in combination with our excellent pre-sale and after-sales service ensures strong competitiveness in an increasingly globalized market. We are willing to cooperate with business friends from at home and abroad and create a great future together.
By Salome from Indonesia - 2018.02.12 14:52
Cooperate with you every time is very successful, very happy. Hope that we can have more cooperation!
By Carol from Grenada - 2018.11.22 12:28