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Wholesale Price Doxycycline Hyclate Dr - Canagliflozin – CPF
Background Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2]. Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1]. Canagliflozin has been ... -
PriceList for Pregabalin Effects - Pitavastatin Calcium – CPF
匹伐他汀钙 Pitavastatin 147526-32-7 In-House PI-5 3800-06-4 In-House PI-6 145516-11-4 In-House PI-7 121660-11-5 In-House Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L... -
Cheap price Telaprevir Supplier - Lenalidomide – CPF
Description Lenalidomide (CC-5013) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Background Lenalidomide ... -
Manufacturing Companies for Doxycycline Mono 100 Mg Tab Tablet - Agomelatine – CPF
Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu... -
New Fashion Design for Daclatasvir 60 Mg - Bictegravir 1611493-60-7 – CPF
Description Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. In Vitro Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integrati... -
Factory Promotional Doxycycline Mono - Pitavastatin Calcium – CPF
匹伐他汀钙 Pitavastatin 147526-32-7 In-House PI-5 3800-06-4 In-House PI-6 145516-11-4 In-House PI-7 121660-11-5 In-House Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L... -
Manufacturer of Metoprolol And Hydrochlorothiazide - LCZ696(Sacubitril + Valsartan) – CPF
Description LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis. Background LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR... -
New Arrival China Sofosbuvir Tablets 400 Mg - LOXO-101 1223403-58-4 – CPF
Background IC50: low nanomolar range for inhibition of all TRK family members LOXO-101 is a tropomyosin receptor kinases (TRK) inhibitor. The TRK family of neurotrophin receptors and their neurotrophin ligands regulate neuron growth, differentiation and survival. In vitro: In previous study, LOXO-101 was evaluated for off-target kinase enzyme inhibition against a panel of non-TRK kinases at a concentration of 1,000 nM and ATP concentrations around the Km. Results showed that LOXO-101 had grea... -
New Delivery for Remdesivir - Rosuvastatin Calcium – CPF
瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP RSM(Crystal) 147118-40-9 In-House RSM(Crude) 147118-40-9 In-House RSP — In-House RS-8 147118-36-3 In-House RS-8-1 147118-37-4 In-House TP-8 131466-61-0 In-House TP-11 147118-35-2 In-House TP-13 147118-39-6 In-House RS-10 289042-12-2 In-House RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a... -
Professional Design Doxycycline Hyclate And Doxycycline Monohydrate - LOXO-101 1223403-58-4 – CPF
Background IC50: low nanomolar range for inhibition of all TRK family members LOXO-101 is a tropomyosin receptor kinases (TRK) inhibitor. The TRK family of neurotrophin receptors and their neurotrophin ligands regulate neuron growth, differentiation and survival. In vitro: In previous study, LOXO-101 was evaluated for off-target kinase enzyme inhibition against a panel of non-TRK kinases at a concentration of 1,000 nM and ATP concentrations around the Km. Results showed that LOXO-101 had grea... -
Manufacturing Companies for Doxycycline Mono 100 Mg Tab Tablet - Baloxavir Marboxil 1985606-14-1 – CPF
Background Baloxavir marboxil is an antiviral drug and is an endonuclease inhibitor. In rats and monkeys, the blood concentration of the drug is lower than the minimum detection amount in a single oral administration of the drug. In preclinical influenza A and B infection models (including strains that are resistant to existing antiviral drugs), Baloxavir marboxil has a certain effect. Chemical Properties Storage Store at -20°C M.Wt 571.55 Cas No. 1985606-14-1 Formula C27H23F2N3O7S ... -
Factory Free sample Canagliflozin Credence - LCZ696(Sacubitril + Valsartan) – CPF
Description LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis. Background LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR...
