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Factory directly Doxycycline Monohydrate 50 Mg - Apixaban – CPF
Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p... -
China Wholesale Brilinta Ticagrelor 90 Mg Suppliers - Ledipasvir Actone /PVP – CPF
雷迪帕韦丙酮/聚维酮 Ledipasvir actone/PVP 1256388-51-8 In-House LPSM1 1256387-87-7 In-House LPSM1-5 291775-59-2 In-House LPSM2 1129634-44-1 In-House LPS-6 1441670-89-8 In-House Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. In Vitro Ledipasvir acetone is considered the active ingredient, which ... -
China Wholesale Ticagrelor 90 Mg Manufacturers - Venetoclax 1257044-40-8 – CPF
维奈妥拉 Venetoclax 1257044-40-8 In-House VCL-6A 98549-88-3 In-House VCL-7A 1235865-75-4 In-House VCLM2 1228780-72-0 In-House VCLM2-2HCl 1628047-87-9 In-House VCLM3 1228779-96-1 In-House Generic Name: venetoclax (ven ET oh klax) Brand Name: Venclexta, Venclexta Starting Pack Venetoclax is used to treat chronic lymphocytic leukemia or small lymphocytic leukemia in adults. Venetoclax is used alone or in combination with other cancer medicines to trea... -
Bottom price Bictegravir Manufacturer - Sugammadex Sodium – CPF
舒更葡糖钠 Sugammadex Sodium 343306-79-6 In-House Description Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block. Generic Name: sugammadex (soo GAM ma dex) Brand Name: Bridion Sugammadex reverses the effects of certain medications that are given during surgical procedures to relax your muscles. Sugammadex is used at the end of surgery, to help restore muscle function that has been blocked during surgery by the other ... -
Top Suppliers Rosuvastatin Calcium Ip - Ribociclib 1374639-75-4 – CPF
Description Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex. In Vitro Treating a panel of 17 neuroblastoma cell lines with Ribociclib (LEE011) across a four-log dose range (10 to 10,000 nM). Treatment with Ribociclib significantly inhibits substrate adherent growth relative to the control in 12 of the 17 neuroblastoma cell lines examined (mean IC50=306±68 nM, con... -
Factory Supply Ticagrelor Tab - Pitavastatin Calcium – CPF
匹伐他汀钙 Pitavastatin 147526-32-7 In-House PI-5 3800-06-4 In-House PI-6 145516-11-4 In-House PI-7 121660-11-5 In-House Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L... -
factory Outlets for Bictegravir - LCZ696(Sacubitril + Valsartan) – CPF
Description LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis. Background LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR... -
OEM China Ticagrelor - Daclatasvir Dihydrochloride – CPF
Description Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively. IC50 & Target EC50: 50 pM (HCV replicon genotype 1a), 9 pM (HCV replicon genotype 1b), 71 pM (HCV replicon genotype 2a), 146 pM (HCV replicon ... -
2020 High quality Ledipasvir - Agomelatine – CPF
Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu... -
China Wholesale Rosuvastatin Calcium Ip Quotes - Captopril – CPF
Description Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). In Vitro Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the c... -
China Wholesale Fenofibrate Rosuvastatin Calcium Manufacturers - Folic Acid – CPF
Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ... -
Newly Arrival Hydrochlorothiazide 25 - Rosuvastatin Calcium – CPF
瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP RSM(Crystal) 147118-40-9 In-House RSM(Crude) 147118-40-9 In-House RSP — In-House RS-8 147118-36-3 In-House RS-8-1 147118-37-4 In-House TP-8 131466-61-0 In-House TP-11 147118-35-2 In-House TP-13 147118-39-6 In-House RS-10 289042-12-2 In-House RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a...
