• Factory directly supply Rosuvastatin Calcium 10 Mg Tab Tablet - Folic Acid  – CPF

    Factory directly supply Rosuvastatin Calcium 10 Mg Tab Tablet - Folic Acid – CPF

    Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ...
  • China Wholesale Rosuvastatin Manufacturer Manufacturers - Thalidomide  – CPF

    China Wholesale Rosuvastatin Manufacturer Manufacturers - Thalidomide – CPF

    Background Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex. Description Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. In Vitro Tha...
  • Factory source Ledipasvir Pvp - Folic Acid  – CPF

    Factory source Ledipasvir Pvp - Folic Acid – CPF

    Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ...
  • OEM Supply Doxycycline Monohydrate Acne - LCZ696(Sacubitril + Valsartan)  – CPF

    OEM Supply Doxycycline Monohydrate Acne - LCZ696(Sacubitril + Valsartan) – CPF

    Description LCZ696 (Sacubitril/Valsartan), comprised Valsartan (an ARB) and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. LCZ696 ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis.   Background LCZ696 is a first in class ARNi (angiotensin receptor neprilysin inhibitor) comprising anionic moieties of AR...
  • China Wholesale Auro Rosuvastatin Calcium Manufacturers - Atorvastatin Calcium  – CPF

    China Wholesale Auro Rosuvastatin Calcium Manufacturers - Atorvastatin Calcium – CPF

    Background Atorvastatin Calcium is a potent inhibitor of HMG-CoA reductase with IC50 value of 150 nM[1]. HMG-CoA reductase is the key enzyme of the mevalonate pathway which produces cholesterol. HMG-CoA is the rate-limiting enzyme and is important for lowering the blood cholesterol levels. HMG-CoA reductase is located in the endoplasmic reticulum and contains eight transmembrane domains. The inhibitors of HMG-CoA reductase can induce the LDL (low density lipoprotein) receptors expression in t...
  • China Wholesale Rosuvastatin Calcium 20 Mg Tablet Manufacturers - Rivaroxaban  – CPF

    China Wholesale Rosuvastatin Calcium 20 Mg Tablet Manufacturers - Rivaroxaban – CPF

    Background Rivaroxaban, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide, is a potent small-molecule inhibitor of factor Xa which is a coagulation factor at a critical juncture in the blood coagulation pathway resulting in the generation of thrombin and the formation of clot. Rivaroxaban binds to the Tyr288 in S1 pocket of factor Xa through the interaction of Tyr288 and the chlorine substituent of the chlorothiophene moiety. The inhi...
  • Renewable Design for Lenalidomide Manufacturer - Ezetimibe  – CPF

    Renewable Design for Lenalidomide Manufacturer - Ezetimibe – CPF

    Background Ezetimibe is a potent and novel inhibitor of cholesterol absorption [1]. Cholesterol is a lipid molecule and is required to build and maintain membranes structural integrity and fluidity. Also, it serves as a precursor of vitamin D, bile acids and steroid hormones. In differentiated Caco-2 cells incubated with a carotenoid (1 μM), ezetimibe (10 mg/L) inhibited carotenoid transport with 50% inhibition for ɑ-carotene and β-carotene. Also, it inhibited the transport of β-cryptoxanthin...
  • Chinese wholesale Sofosbuvir Ns5b - Canagliflozin  – CPF

    Chinese wholesale Sofosbuvir Ns5b - Canagliflozin – CPF

    Background Canagliflozin is a novel, potent, and highly selective sodium glucose co-transporter (SGLT) 2 inhibitor [1]. It has been proved that Canagliflozin can increase urine glucose excretion by reducing the renal glucose threshold and by decreasing the filtered glucose re-absorption [2]. Canagliflozin has been shown to inhibit the Na+-mediated 14C-AMG intakes in CHO-hSGLT2, CHO-rat SGLT2 and CHO-mouse SGLT2 with IC50 values of 4.4, 3.7 and 2.0 nM, respectively [1]. Canagliflozin has been ...
  • China Wholesale Rosuvastatin Calcium 10 Mg Manufacturers - Rosuvastatin Calcium  – CPF

    China Wholesale Rosuvastatin Calcium 10 Mg Manufacturers - Rosuvastatin Calcium – CPF

    瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP     RSM(Crystal) 147118-40-9 In-House     RSM(Crude) 147118-40-9 In-House     RSP — In-House     RS-8 147118-36-3 In-House     RS-8-1 147118-37-4 In-House     TP-8 131466-61-0 In-House     TP-11 147118-35-2 In-House     TP-13 147118-39-6 In-House     RS-10 289042-12-2 In-House     RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a...
  • Factory Cheap Losartan Hydrochlorothiazide 100 Mg 25 Mg - Ticagrelor  – CPF

    Factory Cheap Losartan Hydrochlorothiazide 100 Mg 25 Mg - Ticagrelor – CPF

    Background Ticagrelor is a novel antagonist of the P2Y12 receptor [1]. Ticagrelor has been reported to inhibit the prothrombotic effects of ADP on the platelet by against the P2Y12 receptor. Ticagrelor has shown the complete inhibition of platelet aggregation ex vivo. In addition Ticagrelor has suggested a dose-dependent inhibition of platelet aggregation in human being. Apart from these, Ticagrelor has also demonstrated an orally, actively, reversibly binding antagonist. Unlike other inhibit...
  • China Wholesale Rosuvastatin Calcium 40 Mg Suppliers - Massive Selection for Doxycycline Hyclate 100 Tablet - Captopril  – CPF  – CPF

    China Wholesale Rosuvastatin Calcium 40 Mg Suppliers - Massive Selection for Doxycycline Hyclate 100 Tablet - Captopril – CPF – CPF

    Description Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). In Vitro Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the c...
  • Competitive Price for Olmesartan And Hydrochlorothiazide - Apixaban  – CPF

    Competitive Price for Olmesartan And Hydrochlorothiazide - Apixaban – CPF

    Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p...