• High Quality Doxycycline Hcl Uses - Apixaban  – CPF

    High Quality Doxycycline Hcl Uses - Apixaban – CPF

    Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p...
  • High Quality Ribociclib Manufacturer - Tofacitnib Citrate  – CPF

    High Quality Ribociclib Manufacturer - Tofacitnib Citrate – CPF

    Background Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis.  The inhibition is JAK3 specific with a selectivity 1000-fold more than other non-JAK family kinases. Besides inhibiting JAKS (IC50 = 1 nM), tofacitinib citrate also inhibits janus kinase 2 (JAK2) and janus kinase 1 (JAK1) wit...
  • professional factory for Doxycycline Hyclate Monohydrate - Sacubitril Hemicalcium  – CPF

    professional factory for Doxycycline Hyclate Monohydrate - Sacubitril Hemicalcium – CPF

        沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House     沙库比曲钠盐 149690-05-1 In-House     LCZ-4 1426129-50-1 In-House     LCZ-7 1012341-48-8 In-House     LCZ-8 1012341-50-2 In-House     LCZ-9 149690-12-0 In-House   Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar rati...
  • China Wholesale Rosuvastatin Calcium 5 Mg Tab Tablet Suppliers - Chlorothiazide  – CPF

    China Wholesale Rosuvastatin Calcium 5 Mg Tab Tablet Suppliers - Chlorothiazide – CPF

    Background Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions. Description Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often...
  • High reputation Ticagrelor Uses - Hydrochlorothiazide  – CPF

    High reputation Ticagrelor Uses - Hydrochlorothiazide – CPF

    Description Hydrochlorothiazide (HCTZ), an orally active diuretic drug of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect. Background Hydrochlorothiazide is a diuretic drug of the thiazide class. In Vitro Hydrochlorothiazide belongs to thiazide class of di...
  • 100% Original Lenalidomide - Chlorothiazide  – CPF

    100% Original Lenalidomide - Chlorothiazide – CPF

    Background Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions. Description Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often...
  • Personlized Products Doxycycline Hyclate For Ear Infection - Rosuvastatin Calcium  – CPF

    Personlized Products Doxycycline Hyclate For Ear Infection - Rosuvastatin Calcium – CPF

    瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP     RSM(Crystal) 147118-40-9 In-House     RSM(Crude) 147118-40-9 In-House     RSP — In-House     RS-8 147118-36-3 In-House     RS-8-1 147118-37-4 In-House     TP-8 131466-61-0 In-House     TP-11 147118-35-2 In-House     TP-13 147118-39-6 In-House     RS-10 289042-12-2 In-House     RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a...
  • China Wholesale Ticagrelor 60 Mg Quotes - Sugammadex Sodium  – CPF

    China Wholesale Ticagrelor 60 Mg Quotes - Sugammadex Sodium – CPF

    舒更葡糖钠 Sugammadex Sodium 343306-79-6 In-House Description Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a new reversal agent for neuromuscular block. Generic Name: sugammadex (soo GAM ma dex) Brand Name: Bridion Sugammadex reverses the effects of certain medications that are given during surgical procedures to relax your muscles. Sugammadex is used at the end of surgery, to help restore muscle function that has been blocked during surgery by the other ...
  • China Wholesale Ticagrelor Uses Suppliers - Folic Acid  – CPF

    China Wholesale Ticagrelor Uses Suppliers - Folic Acid – CPF

    Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ...
  • China Wholesale Ticagrelor Classification Factory - Dabigatran Etexilate Mesylate  – CPF

    China Wholesale Ticagrelor Classification Factory - Dabigatran Etexilate Mesylate – CPF

    Description Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active prodrug of Dabigatran. Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation. Background Description: IC50 Value: 4.5nM (Ki); 10nM(Thrombin-induced platelet aggregation) [1] Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) undergoing advanced clinical development as its orally active prodrug,dabiga...
  • China Wholesale Rosuvastatin Calcium 20 Mg Tab Tablet Suppliers - Agomelatine  – CPF

    China Wholesale Rosuvastatin Calcium 20 Mg Tab Tablet Suppliers - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...
  • Personlized Products Remdesivir Supplier - Daclatasvir Dihydrochloride  – CPF

    Personlized Products Remdesivir Supplier - Daclatasvir Dihydrochloride – CPF

    Description Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively. IC50 & Target EC50: 50 pM (HCV replicon genotype 1a), 9 pM (HCV replicon genotype 1b), 71 pM (HCV replicon genotype 2a), 146 pM (HCV replicon ...