• China Wholesale Rosuvastatin Calcium Tablets Ip 10mg Quotes - Folic Acid  – CPF

    China Wholesale Rosuvastatin Calcium Tablets Ip 10mg Quotes - Folic Acid – CPF

    Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ...
  • Excellent quality Obeticholic Acid Indication - Agomelatine  – CPF

    Excellent quality Obeticholic Acid Indication - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...
  • Factory directly Doxycycline Hyclate Generic - Captopril  – CPF

    Factory directly Doxycycline Hyclate Generic - Captopril – CPF

    Description Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). In Vitro Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the c...
  • Manufacturer for Doxycycline Mono Hyclate 100mg - Dabigatran Etexilate Mesylate  – CPF

    Manufacturer for Doxycycline Mono Hyclate 100mg - Dabigatran Etexilate Mesylate – CPF

    Description Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active prodrug of Dabigatran. Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation. Background Description: IC50 Value: 4.5nM (Ki); 10nM(Thrombin-induced platelet aggregation) [1] Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) undergoing advanced clinical development as its orally active prodrug,dabiga...
  • China Wholesale Rosuvastatin Calcium 40 Mg Tablet Factory - Tofacitnib Citrate  – CPF

    China Wholesale Rosuvastatin Calcium 40 Mg Tablet Factory - Tofacitnib Citrate – CPF

    Background Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis.  The inhibition is JAK3 specific with a selectivity 1000-fold more than other non-JAK family kinases. Besides inhibiting JAKS (IC50 = 1 nM), tofacitinib citrate also inhibits janus kinase 2 (JAK2) and janus kinase 1 (JAK1) wit...
  • Wholesale Price China Ramipril 5 Mg Hydrochlorothiazide 12.5 Mg - Atorvastatin Calcium  – CPF

    Wholesale Price China Ramipril 5 Mg Hydrochlorothiazide 12.5 Mg - Atorvastatin Calcium – CPF

    Background Atorvastatin Calcium is a potent inhibitor of HMG-CoA reductase with IC50 value of 150 nM[1]. HMG-CoA reductase is the key enzyme of the mevalonate pathway which produces cholesterol. HMG-CoA is the rate-limiting enzyme and is important for lowering the blood cholesterol levels. HMG-CoA reductase is located in the endoplasmic reticulum and contains eight transmembrane domains. The inhibitors of HMG-CoA reductase can induce the LDL (low density lipoprotein) receptors expression in t...
  • Good Quality Brilinta Ticagrelor 90 Mg - Relugolix 737789-87-6  – CPF

    Good Quality Brilinta Ticagrelor 90 Mg - Relugolix 737789-87-6 – CPF

    Relugolix is used to treat prostate cancer in men. Brand Names: Orgovyx Drug Class: Antineoplastic - LHRH (GnRH) Antagonist Pituitary Suppressants Availability: Prescription Required Pregnancy: Consult your doctor. This medication may be harmful to an unborn child. Lactation: Consult a doctor before using Relugolix is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugo...
  • Factory selling Sofosbuvir 400 Mg - Apixaban  – CPF

    Factory selling Sofosbuvir 400 Mg - Apixaban – CPF

    Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p...
  • 2020 Good Quality Palbociclib Ribociclib - Massive Selection for Doxycycline Hyclate 100 Tablet - Captopril  – CPF  – CPF

    2020 Good Quality Palbociclib Ribociclib - Massive Selection for Doxycycline Hyclate 100 Tablet - Captopril – CPF – CPF

    Description Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). In Vitro Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the c...
  • Big discounting Rosuvastatin Calcium En Español - Obeticholic Acid  – CPF

    Big discounting Rosuvastatin Calcium En Español - Obeticholic Acid – CPF

    Description Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].   Background Obeticholic Acid (6alpha-ethyl-chenodeoxycholic acid, 6-ECDCA, INT-747) is a potent and selective agonist of FXR with EC50 value of 99 nM [1]. The farnesoid X receptor (FXR) is a nuclear bile acid receptor involved in bile acid homeostasis, liver ...
  • OEM/ODM Manufacturer Doxycycline Monohydrate For Strep - Lenalidomide  – CPF

    OEM/ODM Manufacturer Doxycycline Monohydrate For Strep - Lenalidomide – CPF

    Description Lenalidomide (CC-5013) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Background Lenalidomide ...
  • Leading Manufacturer for Bictegravir Cost - Agomelatine  – CPF

    Leading Manufacturer for Bictegravir Cost - Agomelatine – CPF

    Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu...