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Factory Supply Rosuvastatin Calcium 20 Mg Tablet - Ezetimibe – CPF
Background Ezetimibe is a potent and novel inhibitor of cholesterol absorption [1]. Cholesterol is a lipid molecule and is required to build and maintain membranes structural integrity and fluidity. Also, it serves as a precursor of vitamin D, bile acids and steroid hormones. In differentiated Caco-2 cells incubated with a carotenoid (1 μM), ezetimibe (10 mg/L) inhibited carotenoid transport with 50% inhibition for ɑ-carotene and β-carotene. Also, it inhibited the transport of β-cryptoxanthin... -
China Supplier Doxycycline Hyclate 100 Mg Tab Tablet - Rosuvastatin Calcium – CPF
瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP RSM(Crystal) 147118-40-9 In-House RSM(Crude) 147118-40-9 In-House RSP — In-House RS-8 147118-36-3 In-House RS-8-1 147118-37-4 In-House TP-8 131466-61-0 In-House TP-11 147118-35-2 In-House TP-13 147118-39-6 In-House RS-10 289042-12-2 In-House RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a... -
Cheap price Doxycycline Mono For Ear Infection - LOXO-101 1223403-58-4 – CPF
Background IC50: low nanomolar range for inhibition of all TRK family members LOXO-101 is a tropomyosin receptor kinases (TRK) inhibitor. The TRK family of neurotrophin receptors and their neurotrophin ligands regulate neuron growth, differentiation and survival. In vitro: In previous study, LOXO-101 was evaluated for off-target kinase enzyme inhibition against a panel of non-TRK kinases at a concentration of 1,000 nM and ATP concentrations around the Km. Results showed that LOXO-101 had grea... -
China Wholesale Calcium Rosuvastatin Suppliers - Pregabalin – CPF
Pregabalin is not a GABAA or GABAB receptor agonist. Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective i... -
China Wholesale Rosuvastatin Calcium 20 Mg En Español Manufacturers - Sofosbuvir – CPF
索非布韦 Sofosbuvir 1190307-88-0 In-House SFBM 1256490-31-9 In-House SFB-8 874638-80-9 In-House SFB-10 817204-32-3 In-House SFBA-1 863329-66-2 In-House SFBMA 1334513-02-8 In-House Generic Name: sofosbuvir (soe FOS bue vir) Brand Names: Sovaldi Sofosbuvir is an antiviral medicine that is used to treat chronic hepatitis C in adults and children who are at least 3 years old and an HCV RNA replication inhibitor with an EC50 of 92 nM. Sofosbuvir must be... -
Hot New Products Lcz696 Manufacturer - Pitavastatin Calcium – CPF
匹伐他汀钙 Pitavastatin 147526-32-7 In-House PI-5 3800-06-4 In-House PI-6 145516-11-4 In-House PI-7 121660-11-5 In-House Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L... -
OEM/ODM Manufacturer Doxycycline Hyclate For Rosacea - Apixaban – CPF
Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p... -
Factory made hot-sale High Blood Pressure Hydrochlorothiazide - Pregabalin – CPF
Pregabalin is not a GABAA or GABAB receptor agonist. Pregabalin is a gabapentinoid and acts by inhibiting certain calcium channels. Specifically it is a ligand of the auxiliary α2δ subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of α2δ subunit-containing VDCCs. There are two drug-binding α2δ subunits, α2δ-1 and α2δ-2, and pregabalin shows similar affinity for (and hence lack of selectivity between) these two sites. Pregabalin is selective i... -
Lowest Price for Hydrochlorothiazide And Amlodipine - Ledipasvir Actone /PVP – CPF
雷迪帕韦丙酮/聚维酮 Ledipasvir actone/PVP 1256388-51-8 In-House LPSM1 1256387-87-7 In-House LPSM1-5 291775-59-2 In-House LPSM2 1129634-44-1 In-House LPS-6 1441670-89-8 In-House Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. In Vitro Ledipasvir acetone is considered the active ingredient, which ... -
Factory making Celecoxib Supplier - Bictegravir 1611493-60-7 – CPF
Description Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. In Vitro Bictegravir (BIC) inhibits the strand transfer activity with an IC50 of 7.5± 0.3 nM. Relative to its inhibition of strand transfer activity, Bictegravir is a much weaker inhibitor of 3′-processing activity of HIV-1 IN, with an IC50 of 241±51 nM. Bictegravir enhances the accumulation of 2-LTR circles ~5-fold relative to the mock-treated control and reduces the amount of authentic integrati... -
Fast delivery Invokana Canagliflozin - Ticagrelor – CPF
Background Ticagrelor is a novel antagonist of the P2Y12 receptor [1]. Ticagrelor has been reported to inhibit the prothrombotic effects of ADP on the platelet by against the P2Y12 receptor. Ticagrelor has shown the complete inhibition of platelet aggregation ex vivo. In addition Ticagrelor has suggested a dose-dependent inhibition of platelet aggregation in human being. Apart from these, Ticagrelor has also demonstrated an orally, actively, reversibly binding antagonist. Unlike other inhibit... -
China Wholesale Rosuvastatin Calcium 20 Mg En Español Suppliers - Lenalidomide – CPF
Description Lenalidomide (CC-5013) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Background Lenalidomide ...