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China Wholesale Small Log Splitter Quotes - Captopril – CPF
Description Captopril (SQ-14534) is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). In Vitro Captopril (SQ-14534) has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril (SQ-14534) has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[1]. An equimolar ratio of the c... -
Quality Inspection for Lisinopril Hydrochlorothiazide - Ezetimibe – CPF
Background Ezetimibe is a potent and novel inhibitor of cholesterol absorption [1]. Cholesterol is a lipid molecule and is required to build and maintain membranes structural integrity and fluidity. Also, it serves as a precursor of vitamin D, bile acids and steroid hormones. In differentiated Caco-2 cells incubated with a carotenoid (1 μM), ezetimibe (10 mg/L) inhibited carotenoid transport with 50% inhibition for ɑ-carotene and β-carotene. Also, it inhibited the transport of β-cryptoxanthin... -
Reasonable price Rosuvastatin Calcium 40 Mg Tablet - Chlorothiazide – CPF
Background Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions. Description Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often... -
OEM/ODM Supplier Pitavastatin Manufacturer - Pitavastatin Calcium – CPF
匹伐他汀钙 Pitavastatin 147526-32-7 In-House PI-5 3800-06-4 In-House PI-6 145516-11-4 In-House PI-7 121660-11-5 In-House Description Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (L... -
Top Quality Rivaroxaban Supplier - Daclatasvir Dihydrochloride – CPF
Description Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir dihydrochloride is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 µM and 3.27 µM, respectively. IC50 & Target EC50: 50 pM (HCV replicon genotype 1a), 9 pM (HCV replicon genotype 1b), 71 pM (HCV replicon genotype 2a), 146 pM (HCV replicon ... -
China Wholesale Mechanical Log Splitter Manufacturers - Atorvastatin Calcium – CPF
Background Atorvastatin Calcium is a potent inhibitor of HMG-CoA reductase with IC50 value of 150 nM[1]. HMG-CoA reductase is the key enzyme of the mevalonate pathway which produces cholesterol. HMG-CoA is the rate-limiting enzyme and is important for lowering the blood cholesterol levels. HMG-CoA reductase is located in the endoplasmic reticulum and contains eight transmembrane domains. The inhibitors of HMG-CoA reductase can induce the LDL (low density lipoprotein) receptors expression in t... -
2020 Latest Design Lcz696 Supplier - Atorvastatin Calcium – CPF
Background Atorvastatin Calcium is a potent inhibitor of HMG-CoA reductase with IC50 value of 150 nM[1]. HMG-CoA reductase is the key enzyme of the mevalonate pathway which produces cholesterol. HMG-CoA is the rate-limiting enzyme and is important for lowering the blood cholesterol levels. HMG-CoA reductase is located in the endoplasmic reticulum and contains eight transmembrane domains. The inhibitors of HMG-CoA reductase can induce the LDL (low density lipoprotein) receptors expression in t... -
China Wholesale Rosuvastatin Calcium 10 Mg Tab Tablet Quotes - Rosuvastatin Calcium – CPF
瑞舒伐他汀钙 Rosuvastatin Calcium 147098-20-2 In-House/CEP RSM(Crystal) 147118-40-9 In-House RSM(Crude) 147118-40-9 In-House RSP — In-House RS-8 147118-36-3 In-House RS-8-1 147118-37-4 In-House TP-8 131466-61-0 In-House TP-11 147118-35-2 In-House TP-13 147118-39-6 In-House RS-10 289042-12-2 In-House RS-11 355806-00-7 In-House Description Rosuvastatin Calcium (BANM, JAN, USAN) is known as Rosuvastatin in the US. a... -
China Wholesale Ticagrelor Classification Factory - Tofacitnib Citrate – CPF
Background Tofacitinib citrate, also known as CP-690550 citrate, is a potent inhibitor of janus kinase 3 (JAK3), a hematopoetic cell-restricted tyrosine kinase involved in signal transduction regulating lymphocyte survival, proliferation, differentiation, and apoptosis. The inhibition is JAK3 specific with a selectivity 1000-fold more than other non-JAK family kinases. Besides inhibiting JAKS (IC50 = 1 nM), tofacitinib citrate also inhibits janus kinase 2 (JAK2) and janus kinase 1 (JAK1) wit... -
China Wholesale Rosuvastatin Calcium 20 Mg En Español Manufacturers - Agomelatine – CPF
Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu... -
One of Hottest for Doxycycline Hyclate 100mg Ear Infection - Sofosbuvir – CPF
索非布韦 Sofosbuvir 1190307-88-0 In-House SFBM 1256490-31-9 In-House SFB-8 874638-80-9 In-House SFB-10 817204-32-3 In-House SFBA-1 863329-66-2 In-House SFBMA 1334513-02-8 In-House Generic Name: sofosbuvir (soe FOS bue vir) Brand Names: Sovaldi Sofosbuvir is an antiviral medicine that is used to treat chronic hepatitis C in adults and children who are at least 3 years old and an HCV RNA replication inhibitor with an EC50 of 92 nM. Sofosbuvir must be... -
China Gold Supplier for Canagliflozin Class - Sofosbuvir – CPF
索非布韦 Sofosbuvir 1190307-88-0 In-House SFBM 1256490-31-9 In-House SFB-8 874638-80-9 In-House SFB-10 817204-32-3 In-House SFBA-1 863329-66-2 In-House SFBMA 1334513-02-8 In-House Generic Name: sofosbuvir (soe FOS bue vir) Brand Names: Sovaldi Sofosbuvir is an antiviral medicine that is used to treat chronic hepatitis C in adults and children who are at least 3 years old and an HCV RNA replication inhibitor with an EC50 of 92 nM. Sofosbuvir must be...