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2020 wholesale price Sofosbuvir Fda - Ticagrelor – CPF
Background Ticagrelor is a novel antagonist of the P2Y12 receptor [1]. Ticagrelor has been reported to inhibit the prothrombotic effects of ADP on the platelet by against the P2Y12 receptor. Ticagrelor has shown the complete inhibition of platelet aggregation ex vivo. In addition Ticagrelor has suggested a dose-dependent inhibition of platelet aggregation in human being. Apart from these, Ticagrelor has also demonstrated an orally, actively, reversibly binding antagonist. Unlike other inhibit... -
Professional China Doxycycline Mono And Alcohol - Ezetimibe – CPF
Background Ezetimibe is a potent and novel inhibitor of cholesterol absorption [1]. Cholesterol is a lipid molecule and is required to build and maintain membranes structural integrity and fluidity. Also, it serves as a precursor of vitamin D, bile acids and steroid hormones. In differentiated Caco-2 cells incubated with a carotenoid (1 μM), ezetimibe (10 mg/L) inhibited carotenoid transport with 50% inhibition for ɑ-carotene and β-carotene. Also, it inhibited the transport of β-cryptoxanthin... -
China Wholesale Tab Ticagrelor Factory - Agomelatine – CPF
Background Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1]. Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned hu... -
China Wholesale Rosuvastatin Calcium 5 Mg Tab Factory - Sacubitril Hemicalcium – CPF
沙库比曲半钙盐 Sacubitril Hemicalcium 1369773-39-6 In-House 沙库比曲钠盐 149690-05-1 In-House LCZ-4 1426129-50-1 In-House LCZ-7 1012341-48-8 In-House LCZ-8 1012341-50-2 In-House LCZ-9 149690-12-0 In-House Background AHU-377 hemicalcium salt is a hemicalcium salt form of AHU-377. It is an inhibitor of neprilysin with IC50 value of 5 nM [1]. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar ra... -
Special Design for Agomelatine Manufacturer - Apixaban – CPF
Background Apixaban is a highly selective and reversible inhibitor of Factor Xa with Ki values of 0.08 nM and 0.17 nM in human and rabbit, respectively[1]. Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade. Factor X is activated, by hydrolysis, into factor Xa by both factor IX. Factor Xa is the activated form of the coagulation factorthrombokinase.Inhibiting Factor Xa could offer an alternate method for anticoagulation. Direct Xa inhibitors are p... -
Factory best selling Livalo Pitavastatin - Enalapril Maleate – CPF
Background Enalapril Maleate Description Enalapril (maleate) (MK-421 (maleate)), the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. In Vivo Enalapril (MK-421) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to enalaprilat following oral administration. Enalapril (MK-421) is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angio... -
China Wholesale Rosuvastatin Supplier Quotes - Lenalidomide – CPF
Description Lenalidomide (CC-5013) is a derivative of Thalidomide and an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells. Background Lenalidomide ... -
Hot sale Doxycycline Hyclate 100mg For Ear Infection - Velpatasvir(PVP) – CPF
Foreign Names Velpatasvirum (Latin) Velpatasvir (German) Velpatasvir (French) Velpatasvir (Spanish) Generic Names Velpatasvir (OS: USAN) GS-5816 (IS) UNII-KCU0C7RS7Z (IS) Multi-ingredient medications containing velpatasvir:sofosbuvir/velpatasvir systemic Brand names: Epclusa Drug class(es): antiviral combinations Sofosbuvir/velpatasvir systemic is used in the treatment of:Hepatitis C sofosbuvir/velpatasvir/voxilaprevir systemic Brand names: Vosevi Drug class(es): antiviral combinations Sofosb... -
China Wholesale Rosuvastatin Calcium Generic Manufacturers - Doxycycline Hyclate – CPF
Background Doxycycline hyclate is an antibiotic [1]. Doxycycline hyclate is a derivative of tetracycline and possesses the activities of anti-inflammatory and antimicrobial. Doxycycline inhibits dengue virus replication in vitro with a temperature-dependent manner. The IC50 value is 52.3μM at 37°C and 26.7μM at 40°C. It inhibits the dengue virus via inhibiting the NS2B-NS3 serine protease of the virus. 60μM doxycycline reduces the CPE of the DNEV2-infected cells [1]. Doxycycline is found to b... -
China Wholesale Rosuvastatin Calcium Use Factory - Folic Acid – CPF
Background Extracted from Spinacia oleracea;Store the product in sealed, cool and dry condition Description Folic acid(Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Clinical Trial NCT Number Sponsor Condition Start Date Phase NCT03332602 Swiss Federal Institute of Technology Iron-deficiency April 4, 2018 Not Applicable Storage 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, ... -
Original Factory Baloxavir Marboxil - Chlorothiazide – CPF
Background Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions. Description Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often... -
China Wholesale Rosuvastatin Calcium 20 Mg Suppliers - Doxycycline Monohydrate – CPF
多西环素一水物 Doxycycline Monohydrate 17086-28-1 USP/EP Generic Name: doxycycline (DOX i SYE kleen) Brand Names: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs Dosage Form: capsule Doxycycline is a tetracycline antibiotic that fights bacteria in the body and an antibiotic and broad-spectrum metalloproteinase (MMP) inhibi...