China Hot sale Doxycycline Monohydrate 50 Mg Capsule - Agomelatine – CPF manufacturers and suppliers

Hot sale Doxycycline Monohydrate 50 Mg Capsule - Agomelatine – CPF

Short Description:

Product Detail

Product Tags

Feedback (2)

Our goal is usually to deliver high quality items at aggressive price ranges, and top-notch service to shoppers around the entire world. We're ISO9001, CE, and GS certified and strictly adhere to their high quality specifications for Sugammadex Sodium, Doxycycline Hyclate 500mg, Doxycycline Hyclate 200 Mg, We sincerely welcome overseas customers to consult for the long-term cooperation and the mutual development.

Hot sale Doxycycline Monohydrate 50 Mg Capsule - Agomelatine – CPF Detail:

Background

Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1].

Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned human MT1 and MT2 with Ki values of 0.09nM and 0.263nM, respectively. In the in vivo studies, agomelatine causes increase of dopamine and noradrenaline levels via blocking the inhibitory input of 5-HT2C. Moreover, the administration of agomelatine counteractes the stress-induced decrease in sucrose consumption in a rat model of depression. Besides that, agomelatine exerts alleviated anxiety efficacy in a rodent model of anxiety [1].

References:
[1] Zupancic M, Guilleminault C. Agomelatine. CNS drugs, 2006, 20(12): 981-992.

Chemical structure

Agomelatine

2018 GMP-2
原料药GMP证书201811（captopril ,thalidomide etc）
GMP-of-PMDA-in-Chanyoo-平成28年08月03日　Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.

VIEW MORE

VIEW MORE

International cooperation

Domestic cooperation

Product detail pictures:

Related Product Guide:

We not only will try our greatest to supply outstanding services to every shopper, but also are ready to receive any suggestion offered by our buyers for Hot sale Doxycycline Monohydrate 50 Mg Capsule - Agomelatine – CPF , The product will supply to all over the world, such as: belarus, Niger, Brazil, "Make the women more attractive "is our sales philosophy. "Being customers' trusted and preferred brand supplier" is the goal of our company. We've been strict with every part of our work. We sincerely welcome friends to negotiate business and start cooperation. We hope to join hands with friends in different industries to create a brilliant future.

China Wholesale Rosuvastatin Suppliers

China Wholesale Ticagrelor Tab 90 Mg Manufacturers

Doxycycline Hyclate Uses

Doxycycline Mono For Ear Infection

Sofosbuvir 400 Mg Uses

Thalidomide

With a positive attitude of "regard the market, regard the custom, regard the science", the company works actively to do research and development. Hope we have a future business relationships and achieving mutual success.