Newly Arrival Thalidomide Adverse Effects - Pitavastatin Calcium – CPF
Newly Arrival Thalidomide Adverse Effects - Pitavastatin Calcium – CPF Detail:
匹伐他汀钙 | Pitavastatin | 147526-32-7 | In-House |
PI-5 | 3800-06-4 | In-House | |
PI-6 | 145516-11-4 | In-House | |
PI-7 | 121660-11-5 | In-House |
Description
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
Background
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
Storage
4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Chemical structure
Related Biological Data
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
VIEW MORE
VIEW MORE
International cooperation
Domestic cooperation
Product detail pictures:
Related Product Guide:
We've been proud with the significant shopper fulfillment and wide acceptance due to our persistent pursuit of top of the range both of those on solution and repair for Newly Arrival Thalidomide Adverse Effects - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: Honduras, Washington, Japan, We've been always creating new technology to streamline the production, and give products with competitive prices and high quality! Customer satisfaction is our priority! You can let us know your idea to develop unique design for your own model to prevent too much similar parts in the market! We are going to present our best service to satisfy all your needs! Remember to contact us right away!
By Esther from Portugal - 2017.12.09 14:01
The company has rich resources, advanced machinery, experienced workers and excellent services, hope you keep improving and perfecting your products and service, wish you better!
By Olive from Brazil - 2018.06.12 16:22