OEM Customized Niraparib - Chlorothiazide – CPF
OEM Customized Niraparib - Chlorothiazide – CPF Detail:
Background
Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions.
Description
Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often taken in pill form, it is usually taken orally once or twice a day. In the ICU setting, chlorothiazide is given to diurese a patient in addition to furosemide (Lasix). Working in a separate mechanism than furosemide, and absorbed enterically as a reconstituted suspension administered through a nasogastric tube (NG tube), the two drugs potentiate one another.
Clinical Trial
NCT Number | Sponsor | Condition | Start Date |
Phase |
NCT03574857 | University of Virginia | Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure Acute|Cardiovascular Diseases | June 2018 |
Phase 4 |
NCT02546583 | Yale University|National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure | August 2015 |
Not Applicable |
NCT02606253 | Vanderbilt University|Vanderbilt University Medical Center | Heart Failure | February 2016 |
Phase 4 |
NCT00004360 | National Center for Research Resources (NCRR)|Northwestern University|Office of Rare Diseases (ORD) | Diabetes Insipidus, Nephrogenic | September 1995 |
|
NCT00000484 | National Heart, Lung, and Blood Institute (NHLBI) | Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases | April 1966 |
Phase 3 |
Chemical structure
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
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International cooperation
Domestic cooperation
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Our enterprise since its inception, usually regards product top quality as business life, repeatedly enhance manufacturing technology, make improvements to product excellent and continuously strengthen enterprise total high quality administration, in strict accordance with all the national standard ISO 9001:2000 for OEM Customized Niraparib - Chlorothiazide – CPF , The product will supply to all over the world, such as: Namibia, Egypt, belarus, Now, we professionally supplies customers with our main products And our business is not only the "buy" and "sell", but also focus on more. We target to be your loyal supplier and long-term cooperator in China. Now, We hope to be the friends with you.
By Camille from Mozambique - 2017.09.26 12:12
The sales person is professional and responsible, warm and polite, we had a pleasant conversation and no language barriers on communication.
By Marcia from Bhutan - 2017.11.20 15:58