OEM Customized Niraparib - Chlorothiazide – CPF
OEM Customized Niraparib - Chlorothiazide – CPF Detail:
Background
Chlorothiazide is an inhibitor of carbonic anhydrase and is slightly less potent than acetazolamide. This compound has been shown to block reabsorption of sodium and chloride ions.
Description
Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM) Target: Others Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive. Most often taken in pill form, it is usually taken orally once or twice a day. In the ICU setting, chlorothiazide is given to diurese a patient in addition to furosemide (Lasix). Working in a separate mechanism than furosemide, and absorbed enterically as a reconstituted suspension administered through a nasogastric tube (NG tube), the two drugs potentiate one another.
Clinical Trial
NCT Number | Sponsor | Condition | Start Date |
Phase |
NCT03574857 | University of Virginia | Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure Acute|Cardiovascular Diseases | June 2018 |
Phase 4 |
NCT02546583 | Yale University|National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure | August 2015 |
Not Applicable |
NCT02606253 | Vanderbilt University|Vanderbilt University Medical Center | Heart Failure | February 2016 |
Phase 4 |
NCT00004360 | National Center for Research Resources (NCRR)|Northwestern University|Office of Rare Diseases (ORD) | Diabetes Insipidus, Nephrogenic | September 1995 |
|
NCT00000484 | National Heart, Lung, and Blood Institute (NHLBI) | Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases | April 1966 |
Phase 3 |
Chemical structure
Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.
Advanced international quality management system has laid solid foundation for sales.
Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.
Professional Regulatory Affairs team supports the quality demands during the application and registration.
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International cooperation
Domestic cooperation
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We stick to our enterprise spirit of "Quality, Efficiency, Innovation and Integrity". We aim to create more value for our customers with our rich resources, advanced machinery, experienced workers and excellent services for OEM Customized Niraparib - Chlorothiazide – CPF , The product will supply to all over the world, such as: Muscat, Florence, Mexico, We are sincerely looking forward to cooperate with customers all over the world. We believe we can satisfy you with our high-quality products and perfect service . We also warmly welcome customers to visit our company and purchase our products.
By Naomi from Morocco - 2017.08.28 16:02
The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
By Alexandra from Qatar - 2018.02.21 12:14