Wholesale Dealers of Rosuvastatin Calcium 20 Mg Tab Tablet - Agomelatine – CPF

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

"Quality initially, Honesty as base, Sincere company and mutual profit" is our idea, in order to create repeatedly and pursue the excellence for Pregabalin 300, Thalidomide Uses, Hydrochlorothiazide, For more information, please contact us as soon as possible!
Wholesale Dealers of Rosuvastatin Calcium 20 Mg Tab Tablet - Agomelatine – CPF Detail:

Background

Agomelatine is an agonist of melatonin receptors and an antagonist of the serotonin 5-HT2C receptor with Ki values of 0.062nM and 0.268nM and IC50 value of 0.27μM, respectively for MT1, MT2 and 5-HT2C [1].

Agomelatine is a unique antidepressant and is developed for treatment of major depressive disorder (MDD). Agomelatine is selective against 5-HT2C. It shows low affinities to cloned human 5-HT2A and 5-HT1A. For melatonin receptors, agomelatine shows similar affinities to cloned human MT1 and MT2 with Ki values of 0.09nM and 0.263nM, respectively. In the in vivo studies, agomelatine causes increase of dopamine and noradrenaline levels via blocking the inhibitory input of 5-HT2C. Moreover, the administration of agomelatine counteractes the stress-induced decrease in sucrose consumption in a rat model of depression. Besides that, agomelatine exerts alleviated anxiety efficacy in a rodent model of anxiety [1].

References:
[1] Zupancic M, Guilleminault C. Agomelatine. CNS drugs, 2006, 20(12): 981-992.

Chemical structure

Agomelatine

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

OUR STRENGTH

Quality management1

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Quality management2

Advanced international quality management system has laid solid foundation for sales.

Quality management3

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect. 

Quality management4

Professional Regulatory Affairs team supports the quality demands during the application and registration.


VIEW MORE


VIEW MORE

International cooperation
International cooperation
Domestic cooperation
Domestic cooperation


Product detail pictures:

Wholesale Dealers of Rosuvastatin Calcium 20 Mg Tab Tablet - Agomelatine  – CPF detail pictures


Related Product Guide:

Being supported by an advanced and professional IT team, we could offer technical support on pre-sales & after-sales service for Wholesale Dealers of Rosuvastatin Calcium 20 Mg Tab Tablet - Agomelatine – CPF , The product will supply to all over the world, such as: Montpellier, United States, Haiti, We will continue to devote ourselves to market & product development and build a well-knit service to our customer to create a more prosperous future. Please contact us today to find out how we can work together.
  • Hope that the company could stick to the enterprise spirit of "Quality, Efficiency, Innovation and Integrity", it will be better and better in the future.
    5 Stars By Maria from Irish - 2017.06.25 12:48
    Product quality is good, quality assurance system is complete, every link can inquire and solve the problem timely!
    5 Stars By Stephen from Lithuania - 2018.06.28 19:27
    Write your message here and send it to us